The analysis showed that anti-VEGF/VEGFR agents had a significant inhibitory effect on endometriosis score in both rats (SMD –1.13, 95% CI –1.68 to –0.57; P < 0.0001) and mice (SMD –1.49, 95% CI –2.30 to –0.67; P < 0.001). The gene discussed is KDR; the disease is endometriosis.