Careful analysis revealed comparable numbers of total CD8+ T cells and influenza-specific CD8+NP366-372+ and DbPA224-233+ (by tetramer and ICS) in the MLN of Adamts5-/-Vcan+/hdf (versican reduced) and C57.BL6 control mice (Fig 8D–8F). The gene discussed is VCAN; the disease is influenza.