The C-terminal domain of the N protein has been proved to be essential for the interaction with the M protein by yeast two-hybrid binding assay and co-immunoprecipitation in mammalian cells [24], and mutations or deletions in the M gene block the transport of RNP complex to the plasma membrane during infection, further supporting the crucial role of M protein in incorporating the RNP complex into virions [56,57]. The gene discussed is MYOM2; the disease is infection.