Similarly, paclitaxel-carboplatin transiently induces PD-L1 surface protein expression on ovarian cancer patient tumors, and paclitaxel, gemcitabine and carboplatin potentiates surface/intracellular protein, as well as RNA transcription of CD274 in human/mouse ovarian cancer cell lines via NFKβ signaling [43,52]. This evidence concerns the gene CD274 and ovarian cancer.