UCP1 and obesity due to melanocortin 4 receptor deficiency: Besides, the fact of positive correlation between UCP1 expression level in omental fat and EC clinical stage, which is more evident—as was just mentioned—in MHO patients, cannot abolish our earlier data, according to which endometrial cancer clinical stage is more advanced in patients with “standard” (insulin resistance-associated) obesity (Berstein et al. 2015).