We newly found that proinflammatory IL-17+ cells in the peritumoral stroma stimulated hepatoma cells to produce CXCL9, CXCL10 and CXCL11, which in turn led to CXCR3+ B-cell recruitment, maturation and IgG production30. The gene discussed is CXCL11; the disease is hepatocellular carcinoma.