IL10 and hepatocellular carcinoma: In line with our hypothesis, pre-exposure of monocytes to HCC-SN for 1 h in the presence of a hyaluronan-specific blocking peptide (Pep-1) could partially inhibit the semimaturation of DCs (Fig. 3j), as well as subsequent generation of IL-10-producing FcγRIIlow/− B cells Fig. 3k,l).