LAMB2 and Hepatic fibrosis: The effect of fraxinellone was linked to the significant amelioration of BDL- as well as CCl4-induced liver fibrosis in mice, which included improvements of multiple markers, such as adipose degeneration of hepatocytes, fibrous hyperplasia, collagen deposition, serum hyaluronic acid, laminin, type III procollagen, and liver Hyp (Fig. 6).