PDCD4 and digestive system cancer: Low PDCD4 expression was associated with short DFS/RFS of patients with head and neck cancers (HR: 2.10, 95% CI 1.30–3.39) [29], digestive system cancers (HR: 2.57, 95% CI 1.74–3.78) [31, 32], and gynecologic cancers (HR: 3.42, 95% CI 1.41–8.33) [35]; for breast cancer patients, no association was observed (HR: 1.23, 95% CI 0.79–1.92) [30] (Table 3).