Similarly, DEX significantly increased MKP-1 levels in neutrophils from patients with SR asthma by 3.61 ± 0.94-fold (P < 0.05) at 10−6 M and 18.88 ± 7.62-fold (P < 0.01) at 10−4 M relative to control cells (Fig. 1b). Here, DUSP1 is linked to asthma.