Histologically, the breast carcinoma was classified as LBC, with some areas of in situ component, stage pT2 pN2a Mo (5/15 axillary lymph nodes with metastatic disease), and with immunohistochemistry characteristics of Luminal A subtype (ER60%+, PR50%+, HER-2 negative and Ki67 5% positivity). Here, MKI67 is linked to CDH1-related diffuse gastric and lobular breast cancer syndrome.