Kaplan-Meier survival curves graphically also emphasize that the “A/A” genotype of rs9288516 in XRCC5 (X-ray cross-complementing 5) has effect on OS in astrocytomas patients (1-year survival of TT vs. AA: 25% vs.17.9%), which also shorten the astrocytoma patient's survival time, and astrocytoma patients with poor prognosis (HR=1.69) (Figure 1). This evidence concerns the gene XRCC5 and astrocytoma (excluding glioblastoma).