We surmised that: (i) if PLD2 was crucial to migration of xenotransplanted breast cancer cells from the site of xenotransplantation into the circulatory system and beyond into other tissues that have been metastasized (i.e. lungs) and, (ii) if PLD-specific inhibitors reversed this migration, then we would expect to observe a relative decrease in the levels of PLD2 within such tissue. This evidence concerns the gene GPLD1 and breast carcinoma.