Histomorphometry evaluations of VEGF, VEGFR-2 and MMP-9 confirmed the observation of significant decreases (P = .0001) in these markers in endometriosis animals treated with açaí (2.5 ± 0.9, 2.8 ±0.6 and 4.2 ± 0.8, respectively) compared to the control group (22.1 ± 1.1, 25.4 ± 2.5 and 27.5 ± 2.4, respectively). This evidence concerns the gene MMP9 and endometriosis.