ANK1 and parasitic infectious disease: In terms of the response to malaria infection, Ank-1(MRI61689/+) mice exhibited similar degree of malaria resistance as Ank-1(MRI23420/+) and Ank-11674/+ mice, with at least 30–40% reduction in parasitemia and increased survival31, 32, and unlike Ank-1nb/+ mice with only 10% reduction30.