GSDMB and asthma: Based on genotype at rs7216389 (see Supplementary Data set 3)1, located in the gene body of GSDMB, subjects were classified into three groups: (i) homozygous for the asthma-risk allele (TT genotype, n=9), (ii) homozygous for the non-risk allele (CC genotype, n=9) and (iii) carrying heterozygous alleles (TC genotype, n=16).