PIK3CA and cancer: Using a panel of seven well-characterized genes in ECs (ARID1A, PTEN, PIK3CA, KRAS, CTNNB1, PPP2R1A, and TP53), McConechy’s research group compared two morphologically similar cancer types, endometrial endometrioid carcinoma (n = 307) and ovarian endometrioid carcinoma (n = 33) using exon capture sequencing (McConechy et al., 2014).