Beside RE, there are other neurodevelopmental disorders associated with the CTS trait, such as speech disorder (Echenne et al., 1992) developmental coordination disorder (Scabar et al., 2006) and attention deficit-hyperactivity disorder (Holtmann et al., 2003) that could be also linked to Elp4, as in the case of RE. The gene discussed is ELP4; the disease is neurodevelopmental disorder.