In cows with endometritis, serum Hp (ME=154±5.16, E=183±6.2, and SE=234±10.7 μg/ml), SAA (ME=20.25±0.65, E=28.17±1.22, and SE=34.62±1.28 μg/ml), and ceruloplasmin levels (ME=18.57±0.36, E=22.14±0.75, and SE=27.64±0.87 mg/dl) were significantly higher than in healthy cows (72±2.76 μg/ml, 14.24±0.52 μg/ml, and 13.52±0.32 mg/dl, respectively) (p=0.001). Here, HP is linked to endometritis.