For SLE patients, IL-15 enhanced CD11b expression of CD56bright NK subsets (58.8 ± 4.2% versus 50.4 ± 4.9%, p = 0.002) but did not affect that of the CD56dim subsets (52.1 ± 4.2% versus 47.8 ± 4.6%, p = 0.096). The gene discussed is ITGAM; the disease is systemic lupus erythematosus.