In contrast, IL-15 resulted in a decrease in CD62L expression on NK cells from both SLE patients (5619 ± 1357 versus 9226 ± 1395, p = 0.028) and controls (4482 ± 552 versus 5617 ± 658, p = 0.001). The gene discussed is SELL; the disease is systemic lupus erythematosus.