IL-15 resulted in a decrease in CD62L MFI on NKT-like cells from both SLE patients (9213 ± 1150 versus 14565 ± 1392, p < 0.001) and controls (13151 ± 1214 MFI versus 16676 ± 1630, p = 0.002). This evidence concerns the gene SELL and systemic lupus erythematosus.