That can be the result from the fact that 10% of NETs will be associated with an inherited genetic syndromes, such as MEN1 (hyperparathyroidism, pancreatic NETs in up to 75% of cases, and pituitary tumors), Von Hippel-Lindau disease (NF-pancreatic NETs) in 10–20% of patients, cystadenomas, hemangioblastomas and adenocarcinoma, tuberous sclerosis, and NF1 [10]. Here, NF1 is linked to pancreatic neuroendocrine tumor.