The PD-L1-high group contained two EGFR-mutant and five KRAS-mutant cell lines, the histological characteristics of which resulted six of them being classified as adenocarcinomas and one as a large cell carcinoma, while the PD-L1-low group contained only two KRAS-mutant adenocarcinoma cell lines (Table 1). This evidence concerns the gene KRAS and large cell carcinoma.