Although there are no differences in the extent of blood pressure lowering between types of antihypertensive drugs, certain classes of drugs are postulated to potentially confer a greater amount of cerebroprotection than others.[1] Fournier et al in 2004 [1] has reinforced the possible role of angiotensin II (Ang II) in stroke protection after it was first proposed by Brown and Brown [2] in 1986. The gene discussed is AGT; the disease is Stroke.