Staining for Angpt1 was not significantly different (0.26% vs. 0.11%; p = 0.11), but the Angpt2 expression was significantly lower in CKD children (0.91% vs. 0.21%; p = 0.0137) (Figs 4 and 5), resulting in a ratio of Angpt1/Angpt2 of 0.85 ± 1.2 in CKD and of 0.25 ± 0.25 in controls (p = 0.19). This evidence concerns the gene ANGPT1 and chronic kidney disease.