The WB analysis from each of the PCOS (n = 10) and control patients (n = 10) exhibited a significant (P<0.01) increase in the expression of PGRMC1, RBP1, HSP90B1, and CALM1 and a significant (P<0.05) decrease in the expression of ANXA6 and TPM2 in the ovary of PCOS in comparison to the control patients (S3B Fig). Here, PGRMC1 is linked to polycystic ovary syndrome.