Most of the basal miRNAs targeted factors that have been implicated in the control of luminal biology (FOXA1, ERBB2), adipogenesis (FGFR2, FGFR3) and urothelial differentiation (HOX5/8/13), all of which would be predicted to be suppressed in basal cancers. This evidence concerns the gene FGFR3 and cancer.