The growth kinetics of MDA-MB-231 and MCF-7 xenografts suggested that TRIM28 depletion led to the inhibition of tumor growth in MDA-MB-231 cells (p = 1E-04), which have a high percentage of CD44+/CD24−/low cells, but not in MCF-7, which have a very low number of CD44+/CD24−/low cells (Figure 4, upper panel). The gene discussed is CD44; the disease is neoplasm.