Her-2, EGFR, TOPIIα, P170, Ki67, CA199, CEA, ERCC1, MLH1, MSH2, CDX2, nm23, PTEN and survivin are routine pathological molecular markers that are evaluated by immunohistochemistry in the department of pathology as required to diagnose CRC (Fig. 4). This evidence concerns the gene MKI67 and colorectal carcinoma.