In the EnSCs/SK-OV-3 xenografted tumor tissues, we observed that the levels of both VEGFA (Fig. 7C, n = 5) and HIF-1α (Fig. 7D, n = 5) was significantly decreased compared with that of SK-OV-3 injected group using IHC analysis, indicating that EnSCs exerted inhibitory effects on the pro-angiogenetic ability of EOC cells in vivo. Here, HIF1A is linked to neoplasm.