MLH1 and neoplasm: Ahn et al., [45] identified wingless-type MMTV integration site family, member 5A (WNT5A), secreted frizzled-related protein 1 (SFRP1), secreted frizzled-related protein 2 (SFRP2), human mutL homolog 1 (hMLH1), p16, p14, methylated in tumor (MINT1, MINT2, and MINT31) to be good prognostic markers of CIMP+ CRC.