Increased expression of Wnt ligands was reported in breast cancer [30] and dishevelled in cervical cancer [31], while decreased expression of dickkopf-1 was reported in pancreatic cancer [32], secreted frizzled-related protein 1 (SFRP1) in lung cancer [33], and WIF1 in cervical cancer [6]. The gene discussed is FRZB; the disease is familial pancreatic carcinoma.