INS and type 1 diabetes mellitus: The mean insulin dose in antibodies-negative patients was significantly lower than in patients with at least one positive antibody in the whole cohort (0.63 (0.4) vs. 0.77 (0.4), p = 0.001, respectively) (Table 2), and also in the subcohort with newly diagnosed T1D patients (0.43 (0.3) vs. 0.71 (0.4), p = 0.002, respectively) (Table 3).