CD274 and non-small cell lung carcinoma: In a pooled analysis including advanced NSCLC patients who were pre-screened and/or enrolled in three trials evaluating the anti-PD-L1 antibody atezolizumab (PCD4989g Phase Ia; FIR Phase II; POPLAR Phase II; 1,273 patients), high expression of the receptors PD-1 and B7.1 was associated with improvement in OS following treatment with atezolizumab.