UBAP1 and nasopharyngeal carcinoma: UBAP1 is an ubiquitin-binding ESCRT-I subunit that acts exclusively in MVB sorting (Stefani et al., 2011, Wunderley et al., 2014) and, like for HD-PTP (Cheng et al., 1998, Toyooka et al., 2000), haploinsufficiency of UBAP1 is linked to nasopharyngeal carcinoma (Qian et al., 2001).