Although ARS is most commonly caused by heterozygous mutations in FOXC1 (forkhead box C1) (MIM: 601090) and PITX2 (pituitary homeobox 2) (MIM: 601542),4, 5, 6, 7FOXC1 and PITX2 have also been associated with Peters anomaly (MIM: 604229)5, 8 and some cases of aniridia (MIM: 106210).9 This evidence concerns the gene FOXC1 and isolated aniridia.