BRCA1 and breast neoplasm: Following both sets of analyses and including our previously published data, one breast tumor (case 8) and one OC (case 2) showed LOH for BRCA1, two breast tumors (cases 9 and 11) showed LOH of BRCA2, and the remaining tumors provided no evidence for LOH at either BRCA1 or BRCA2 (Table 5).