Overall survival analysis of ER positive patients of the TCGA data set revealed that those with high KCNJ3 levels in the tumor (group C) had shorter overall survival times than patients of group B with low KCNJ3 levels (n = 647; p < 0.05; HR = 1.77 (1.04–3.02); Figure 5A). Here, ESR1 is linked to neoplasm.