In the case of regulatory subunits, MCF10 epithelial cells had higher p85α than p85β levels; the H1703 adenocarcinoma, and three of the ten SQCC lines (HCC15, H1869, H2170) had similar p85α and p85β levels; the remaining seven SQCC lineshad higher levels of p85β, with p85β/p85α ratios varying from 2 to >10 (Figure 1B). Here, PIK3R2 is linked to adenocarcinoma.