IFITM3 and neoplasm: Further, the overall survival of the mice orthotopically implanted with the respective tumor cells as described above was monitored but the ectopic expression of IFITM3-myc did not change the survival of mice transplanted with 1080 cells (Figure 5E; median survival 63 vs 66 d in control animals; n = 10; P > 0.05) or 1075 cells (Figure 5F; median survival 64 vs 66 d in control animals; n = 10; P > 0.05).