As observed in NSCLC cell lines, no correlations were identified between the basal mRNA expression of BRD2, 3 or 4, histones (HIST2H2BE, HIST1H2BJ, HIST1H2BK and HIST2H4A), MYC, MYCN, BCL2, P21, HEXIM1, SESN3 and MTHFD1L nor after 24 h with OTX015 in SCLC cell lines (Supplementary Figure S2B). This evidence concerns the gene CDKN1A and non-small cell lung carcinoma.