PPARA and central nervous system cancer: We determined the direct interaction between miR-19a and its binding site within PPARα mRNA, usingluciferase reporter constructs containing either wild-type (pGL3-WT- PPARα-3′UTR) or mutant (pGL3-MUT- PPARα-3′UTR) PPARα 3′UTRs transfected into glioma cells.