IRF8 and systemic lupus erythematosus: We also observed dysregulation of transcripts associated with Cell Cycle Arrest/ ER stress (Unfolded protein response)/ Regulatory molecules/ Transcription factors Genes like IRF4, STAT6, ID3, ICSBP (IRF8), CD9, GADD45A, GADD45G, HERPUD1, ERO1L, PDIA3, DNAJC10, DNAJC4, TNFRSF14 (CD270), LAIR1 (CD305), SLAMF7 (CD319), VDR, FYN, FKBP11, BCL11A, HLA-DMB, HLA-DMA and PCNA either in one or more subset of SLE patients (Table 5).