The significant association was not affected after adjusting for the additional variables including ALT, AST, serum creatinine, TG, TC, HDL-C, LDL-C and anti-hypertension, anti-diabetes and anti-hyperlipidemia medicine (RR Q1 vs Q4, 3.16; 95% CI, 1.59–6.28). This evidence concerns the gene GPT and hypertensive disorder.