Research showed that Gankyrin was expressed in almost all eukaryotic cells, especially in many kinds of cancers, such as hepatocellular carcinoma (HCC) [19, 20], CRC [21, 22], esophageal squamous cell carcinoma (ESCC) [23], lung cancers [24], and breast cancer [25]. This evidence concerns the gene PSMD10 and esophageal squamous cell carcinoma.