TNF and familial pancreatic carcinoma: Again, TNF-α independently and significantly predicted outcomes in all pancreatic cancer cases as well as PDAC cases (HR = 1.735, 95% CI: 1.046-2.877, P = 0.0327; HR = 1.868, 95% CI: 1.097–3.183, P = 0.0214, respectively; Table 1).