Furthermore, YAP1 (located on 11q22) has been identified as a candidate oncogene in several cancers; its overexpression and increased nuclear localization have been reported in breast cancer [8], hepatocellular carcinoma [10], colorectal cancer [11], GC [12], pancreatic cancer [13], and esophageal squamous cell carcinoma [14]. Here, YAP1 is linked to cancer.