For II-IIIa tumour stages, a negative impact of Orai3 expression was observed on OS (Figure 2E, median 25.60 months for high Orai3 vs. 50.73 months for low Orai3 expression, p=0.02; log rank test), but not on MFS (Figure 2F). The gene discussed is ORAI3; the disease is neoplasm.