HNF4A and cancer: Inappropriate activation of WNT signaling leads to functional disruption of the β-catenin degradation complex and accumulation of free pool of β-catenin in cytoplasm or nucleus where the unphosphorylated (“activated”) β-catenin promotes the transcription of specific WNT target genes by binding to TCF transcription factors in the nucleus, which are the basis for WNT-induced changes in cancer progression and development [59–67].