Immunoblotting analysis also showed effective inhibition of the EMT phenotype by KY1022, with decreased levels of β-catenin, pan-Ras, K-Ras, p-ERK, and p-AKT in the small intestinal tumors of APCMin/+/K-RasG12DLA2 mice (Figure 7C). Here, AKT1 is linked to small intestine neoplasm.