MAPT and cancer: However, in my view, similar (maybe a bit less detailed) essays can be easily drafted for several other pathology-associated proteins, such as cancer-related PTEN, BRCA1, androgen receptor, DMP1, Mdm2, proteins from the Wnt pathway, and HER2, or neurodegeneration-related α-synuclein, FUS, TDP43, huntingtin, and tau protein, to name a few.