PGP and cervical carcinoma: Two years later, the same group [35] purified the three major curcuminoids from the previously-used curcumin mixture [34] (curcumin, demethoxycurcumin, and bisdemethoxycurcumin, Figure 2) and analyzed the effect of the three curcuminoids on the modulation of P-gp function in the same MDR human cervical carcinoma cell line [35].